Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC1 All Species: 13.33
Human Site: S359 Identified Species: 26.67
UniProt: P35251 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35251 NP_002904.3 1148 128255 S359 K T P K K T K S S P A K K E S
Chimpanzee Pan troglodytes XP_001140765 1148 128250 S359 K T P K K T K S S P A K K E S
Rhesus Macaque Macaca mulatta XP_001091287 1148 128475 S359 K T P K K T K S S P A K K E S
Dog Lupus familis XP_536259 1145 128125 S356 K T P K K P K S S P A K K E S
Cat Felis silvestris
Mouse Mus musculus P35601 1131 125967 V356 T T P K K T K V S P T K R E S
Rat Rattus norvegicus NP_445999 1131 125770 G354 T T P R K T K G S P T K R E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512744 1233 136122 V442 R S P K K S N V S S S K S E S
Chicken Gallus gallus NP_001006456 1147 128454 I356 R T P K K E K I S P K K A E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35600 986 108596 V259 E R E E A E S V I K E Y G G K
Honey Bee Apis mellifera XP_397246 911 103001 K184 Q H K K T S S K K M D T S D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797949 906 99249 K179 K G K G L A S K L A A K V K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38630 861 94885 A134 A K F D F K S A N S N A D P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 89.3 N.A. 82.4 81.3 N.A. 67.4 68.9 N.A. N.A. N.A. 39.9 36.2 N.A. 38
Protein Similarity: 100 99.6 98.5 93.7 N.A. 89.5 88.5 N.A. 77.2 79.6 N.A. N.A. N.A. 55.9 53.6 N.A. 52.2
P-Site Identity: 100 100 100 93.3 N.A. 73.3 66.6 N.A. 46.6 66.6 N.A. N.A. N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 73.3 73.3 N.A. N.A. N.A. 13.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 9 0 9 0 9 42 9 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 0 0 9 0 9 9 9 % D
% Glu: 9 0 9 9 0 17 0 0 0 0 9 0 0 67 0 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 9 0 0 0 0 9 9 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 9 % I
% Lys: 42 9 17 67 67 9 59 17 9 9 9 75 34 9 9 % K
% Leu: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 9 0 9 0 0 0 0 % N
% Pro: 0 0 67 0 0 9 0 0 0 59 0 0 0 9 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 17 9 0 9 0 0 0 0 0 0 0 0 17 0 0 % R
% Ser: 0 9 0 0 0 17 34 34 67 17 9 0 17 0 67 % S
% Thr: 17 59 0 0 9 42 0 0 0 0 17 9 0 0 0 % T
% Val: 0 0 0 0 0 0 0 25 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _